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USC-OGP 2-DE database
Two-dimensional polyacrylamide gel electrophoresis database
USC-OGP 2-DE database
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Searching in 'USC-OGP 2-DE database' for entry
matching:
P31146
USC-OGP 2-DE database
:
P31146
P31146
General information about the entry
View entry in simple text format
Entry name
COR1A_HUMAN
Primary accession number
P31146
integrated into USC-OGP 2-DE database on
January 17, 2017 (release 1)
2D Annotations were last modified on
January 17, 2017 (version 1)
General Annotations were last modified on
April 5, 2017 (version 2)
Name and origin of the protein
Description
RecName: Full=Coronin-1A; AltName: Full=Coronin-like protein A; Short=Clipin-A; AltName: Full=Coronin-like protein p57; AltName: Full=Tryptophan aspartate-containing coat protein; Short=TACO;.
Gene name
Name=CORO1A
Synonyms=CORO1
Annotated species
Homo sapiens (Human) [TaxID:
9606
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]
2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein
PLATELET_6-11
{PLATELET 6-11}
Homo sapiens (Human)
map experimental info
PLATELET_6-11
MAP LOCATIONS:
SPOT OGP-0893
:
pI=6.15; Mw=53506
Cross-references
UniProtKB/Swiss-Prot
P31146; COR1A_HUMAN.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
0.0
Entry name
COR1A_HUMAN
Primary accession number
P31146
Secondary accession number(s)
B2RBL1 Q2YD73
Sequence was last modified on
January 23, 2007 (version 4)
Annotations were last modified on
March 15, 2017 (version 168)
Name and origin of the protein
Description
RecName: Full=Coronin-1A; AltName: Full=Coronin-like protein A; Short=Clipin-A; AltName: Full=Coronin-like protein p57; AltName: Full=Tryptophan aspartate-containing coat protein; Short=TACO;
Gene name
Name=CORO1A
Synonyms=CORO1
Encoded on
Name=CORO1A; Synonyms=CORO1
Keywords
Acetylation
;
Actin-binding
;
Coiled coil
;
Complete proteome
;
Cytoplasm
;
Cytoplasmic vesicle
;
Cytoskeleton
;
Direct protein sequencing
;
Disease mutation
;
Membrane
;
Phosphoprotein
;
Polymorphism
;
Reference proteome
;
Repeat
;
Ubl conjugation
;
WD repeat
.
Copyright
Copyrighted by the UniProt Consortium, see
http://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
D44497; BAA07940.1
; -; mRNA
EMBL
X89109; CAA61482.1
; -; mRNA
EMBL
U34690; AAA77058.1
; -; mRNA
EMBL
AF495470; AAM18516.1
; -; mRNA
EMBL
AK314714; BAG37258.1
; -; mRNA
EMBL
CH471238; EAW79906.1
; -; Genomic_DNA
EMBL
BC110374; AAI10375.1
; -; mRNA
EMBL
BC126385; AAI26386.1
; -; mRNA
EMBL
BC126387; AAI26388.1
; -; mRNA
CCDS
CCDS10673.1; -
; .
PIR
S65665; S65665
; .
RefSeq
NP_001180262.1; NM_001193333.2
; .
RefSeq
NP_009005.1; NM_007074.3
; .
RefSeq
XP_011544016.1; XM_011545714.2
; .
UniGene
Hs.415067; -
; .
ProteinModelPortal
P31146; -
; .
SMR
P31146; -
; .
BioGrid
116322; 49
; .
IntAct
P31146; 24
; .
MINT
MINT-263387; -
; .
STRING
9606.ENSP00000219150; -
; .
iPTMnet
P31146; -
; .
PhosphoSitePlus
P31146; -
; .
SwissPalm
P31146; -
; .
BioMuta
CORO1A; -
; .
DMDM
1706004; -
; .
OGP
P31146; -
; .
UCD-2DPAGE
P31146; -
; .
EPD
P31146; -
; .
MaxQB
P31146; -
; .
PaxDb
P31146; -
; .
PeptideAtlas
P31146; -
; .
PRIDE
P31146; -
; .
TopDownProteomics
P31146; -
; .
DNASU
11151; -
; .
Ensembl
ENST00000219150; ENSP00000219150
; ENSG00000102879; .
Ensembl
ENST00000570045; ENSP00000455552
; ENSG00000102879; .
GeneID
11151; -
; .
KEGG
hsa:11151; -
; .
UCSC
uc002dww.4; human
; .
CTD
11151; -
; .
DisGeNET
11151; -
; .
GeneCards
CORO1A; -
; .
HGNC
HGNC:2252; CORO1A
; .
HPA
CAB046473; -
; .
HPA
HPA051132; -
; .
MalaCards
CORO1A; -
; .
MIM
605000; gene
; .
MIM
615401; phenotype
; .
neXtProt
NX_P31146; -
; .
OpenTargets
ENSG00000102879; -
; .
Orphanet
228003; Severe combined immunodeficiency due to CORO1A deficiency
; .
PharmGKB
PA26768; -
; .
eggNOG
KOG0303; Eukaryota
; .
eggNOG
ENOG410XQAD; LUCA
; .
GeneTree
ENSGT00760000119195; -
; .
HOGENOM
HOG000166356; -
; .
HOVERGEN
HBG059978; -
; .
InParanoid
P31146; -
; .
KO
K13882; -
; .
OMA
HAVFVSE; -
; .
OrthoDB
EOG091G03H5; -
; .
PhylomeDB
P31146; -
; .
TreeFam
TF314280; -
; .
SignaLink
P31146; -
; .
SIGNOR
P31146; -
; .
GeneWiki
CORO1A; -
; .
GenomeRNAi
11151; -
; .
PRO
PR:P31146; -
; .
Proteomes
UP000005640; Chromosome 16
; .
Bgee
ENSG00000102879; -
; .
CleanEx
HS_CORO1A; -
; .
ExpressionAtlas
P31146; baseline and differential
; .
Genevisible
P31146; HS
; .
GO
GO:0005884; C:actin filament
; IDA:UniProtKB; .
GO
GO:0030424; C:axon
; IEA:Ensembl; .
GO
GO:0005911; C:cell-cell junction
; IEA:Ensembl; .
GO
GO:0030864; C:cortical actin cytoskeleton
; IDA:UniProtKB; .
GO
GO:0005737; C:cytoplasm
; IDA:UniProtKB; .
GO
GO:0005829; C:cytosol
; IEA:GOC; .
GO
GO:0005769; C:early endosome
; IEA:Ensembl; .
GO
GO:0070062; C:extracellular exosome
; IDA:UniProtKB; .
GO
GO:0001772; C:immunological synapse
; IDA:UniProtKB; .
GO
GO:0030027; C:lamellipodium
; IDA:UniProtKB; .
GO
GO:0016020; C:membrane
; IDA:UniProtKB; .
GO
GO:0001891; C:phagocytic cup
; IDA:UniProtKB; .
GO
GO:0045335; C:phagocytic vesicle
; IDA:UniProtKB; .
GO
GO:0030670; C:phagocytic vesicle membrane
; IEA:UniProtKB-SubCell; .
GO
GO:0005886; C:plasma membrane
; IDA:UniProtKB; .
GO
GO:0043234; C:protein complex
; IDA:UniProtKB; .
GO
GO:0003779; F:actin binding
; IPI:UniProtKB; .
GO
GO:0051015; F:actin filament binding
; IDA:UniProtKB; .
GO
GO:0003785; F:actin monomer binding
; IMP:UniProtKB; .
GO
GO:0008092; F:cytoskeletal protein binding
; ISS:UniProtKB; .
GO
GO:0032036; F:myosin heavy chain binding
; IPI:UniProtKB; .
GO
GO:0043548; F:phosphatidylinositol 3-kinase binding
; IDA:UniProtKB; .
GO
GO:0008022; F:protein C-terminus binding
; IPI:UniProtKB; .
GO
GO:0042803; F:protein homodimerization activity
; IDA:UniProtKB; .
GO
GO:0003723; F:RNA binding
; IDA:UniProtKB; .
GO
GO:0030036; P:actin cytoskeleton organization
; IMP:UniProtKB; .
GO
GO:0007015; P:actin filament organization
; IEA:Ensembl; .
GO
GO:0006816; P:calcium ion transport
; IEA:Ensembl; .
GO
GO:0031589; P:cell-substrate adhesion
; IMP:UniProtKB; .
GO
GO:0071353; P:cellular response to interleukin-4
; IEA:Ensembl; .
GO
GO:0061502; P:early endosome to recycling endosome transport
; IEA:Ensembl; .
GO
GO:0048873; P:homeostasis of number of cells within a tissue
; IEA:Ensembl; .
GO
GO:0045087; P:innate immune response
; NAS:UniProtKB; .
GO
GO:0030595; P:leukocyte chemotaxis
; IEA:Ensembl; .
GO
GO:0006928; P:movement of cell or subcellular component
; NAS:UniProtKB; .
GO
GO:0043320; P:natural killer cell degranulation
; IMP:UniProtKB; .
GO
GO:0051126; P:negative regulation of actin nucleation
; IDA:UniProtKB; .
GO
GO:0043524; P:negative regulation of neuron apoptotic process
; IEA:Ensembl; .
GO
GO:0031339; P:negative regulation of vesicle fusion
; IEA:Ensembl; .
GO
GO:0038180; P:nerve growth factor signaling pathway
; IEA:Ensembl; .
GO
GO:0006909; P:phagocytosis
; IMP:UniProtKB; .
GO
GO:0001845; P:phagolysosome assembly
; IMP:UniProtKB; .
GO
GO:0050918; P:positive chemotaxis
; IDA:UniProtKB; .
GO
GO:0030335; P:positive regulation of cell migration
; IEA:Ensembl; .
GO
GO:0042102; P:positive regulation of T cell proliferation
; IEA:Ensembl; .
GO
GO:0032956; P:regulation of actin cytoskeleton organization
; IMP:UniProtKB; .
GO
GO:0008360; P:regulation of cell shape
; IEA:Ensembl; .
GO
GO:0051279; P:regulation of release of sequestered calcium ion into cytosol
; IEA:Ensembl; .
GO
GO:0043029; P:T cell homeostasis
; IEA:Ensembl; .
GO
GO:0032796; P:uropod organization
; IEA:Ensembl; .
Gene3D
2.130.10.10; -
; 1; .
InterPro
IPR029508; CORO1A
; .
InterPro
IPR015505; Coronin
; .
InterPro
IPR015048; DUF1899
; .
InterPro
IPR015049; Trimer_CC
; .
InterPro
IPR015943; WD40/YVTN_repeat-like_dom
; .
InterPro
IPR001680; WD40_repeat
; .
InterPro
IPR019775; WD40_repeat_CS
; .
InterPro
IPR017986; WD40_repeat_dom
; .
PANTHER
PTHR10856; PTHR10856
; 1; .
PANTHER
PTHR10856:SF31; PTHR10856:SF31
; 1; .
Pfam
PF08953; DUF1899
; 1; .
Pfam
PF08954; Trimer_CC
; 1; .
Pfam
PF00400; WD40
; 3; .
SMART
SM01166; DUF1899
; 1; .
SMART
SM00320; WD40
; 3; .
SUPFAM
SSF50978; SSF50978
; 1; .
PROSITE
PS00678; WD_REPEATS_1
; 2; .
PROSITE
PS50082; WD_REPEATS_2
; 2; .
PROSITE
PS50294; WD_REPEATS_REGION
; 1; .
Gateways to other related servers
The World-2DPAGE Constellation
- Entry point to the world-wide 2-DPAGE resources.
World-2DPAGE Repository
- A public repository for gel-based proteomics data linked to protein identification published in the literature.
World-2DPAGE Portal
- A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
SWISS-2DPAGE
- The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
ExPASy
- The resources web server of the
Swiss Institute of Bioinformatics
Database constructed and maintained by
Angel Garcia
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server
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